Comprehensive gene/variant summaries for neuropsychiatric & metabolic pathways | Sources: PubMed, OMIM, KEGG, NCBI Gene, Reactome
These genes span multiple pathways and represent well-replicated GWAS signals, emerging risk loci, and pharmacogenetic targets.
Dopamine synthesis, transport, receptor signaling, and degradation. Central to reward, motivation, motor control, and executive function.
Serotonergic neurotransmission, synthesis, reuptake, and receptor-mediated signaling. Implicated in mood, anxiety, impulsivity, and appetite.
NMDA/AMPA receptor subunits, voltage-gated calcium channels, and downstream synaptic plasticity cascades.
Genes involved in energy homeostasis, adiposity, insulin signaling, and chronic low-grade inflammation that interface with brain health.